Curriculum Vitae

Marie Plante

Titre Medical
Gynecologue Oncologue Professeur Aggregee

Titre Universitaire
Chef, Service de Gynecologie Oncologique

Affiliation Universitaire
Departement d'Obstetrique-Gynecologie, Faculte de Medecine

Diplomes

 

Medecine, Universite Laval, 1986

Obstetrique et Gynecologie, Universite McGill, 1990

Oncologie Gynecologique (fellowship), Memorial Sloan Kettering Cancer Center, New York, 1993

Telephone (bureau) 418-691-5392

Telecopie 418-691-5720

Champs d'intérêts

 

Le Dr Marie Plante a complete une surspecialite de 3 ans en oncologie gynecologique.

Ses principaux centres d'interets sont en chirurgie dite minimalement invasive, i.e. chirurgie laparoscopique avancee et chirurgie vaginale radicale. Elle est particulierement interessee aux techniques chirurgicales et traitements conservateurs visant le maintien de la fertilite chez les jeunes femmes atteintes de cancers gynecologiques.

Le Dr Plante a egalement un interet au niveau des cancers hereditaires du sein et de l'ovaire. Elle dirige la clinique des cancers hereditaires de l'ovaire a L'Hotel-Dieu de Quebec.

Projets

   

Trachelectomie radicale vaginale dans le traitement du cancer du col uterin chez les jeunes femmes atteintes de cancer du col uterin de stade debutant.

Chimiotherapie neoadjuvante suivie de la trachelectomie radicale chez les jeunes femmes atteintes d'un cancer du col uterin localement avance.

Laparoscopie retroperitoneale dans le stadage des cancers gynecologiques.

Publications

1993

S.Rubin, C. Finstad, G. Wong, L. Almadrones, M. Plante, K. Lloyd. Prognostic significance of HER-2/neu expression in advanced epithelial ovarian cancer: a multivariate analysis. American Journal of Obstetrics & Gynecology 168; 162-9, 1993.

G. Gastl,M. Plante, C. Finstad, G. Wong, M. Federici, N. Bander, S. Rubin. High IL-6 levels in ascitic fluid correlated with reactive thrombocytosis in patients with epithelial ovarian cancer. British Journal of Haematology 83; 433-41, 1993.

M. Plante, G. Wong, J. Nisselbaum, L. Almadrones, W. Hoskins, S.C Rubin. Relationship between saliva and serum CA 125 levels in women with and without epithelial ovarian cancer. Obstetrics and Gynecology 81; 989-92, 1993.

1994

M. Plante, S.Rubin, G. Wong, C. Finstad, M. Federici, G.Gastl. IL-6 level in serum and ascites as prognostic factor in women with epithelial ovarian cancer. Cancer 73; 1882-8, 1994.

1995

Plante M. and Roy M. The use of operative laparoscopy in determining eligibility for pelvic exenteration in patients with recurrent cervical cancer. Gynecol Oncol 59;410-4,1995.

1996

Roy M, Plante M, Renaud M-C and Têtu B. Vaginal radical hysterectomy versus abdominal radical hysterectomy in the treatment of early-stage cervical cancer. Gynecol Oncol 62; 336-339, 1996.

1997

Rhode D, Gastl G, Biesterfeld S, Plante M and Jakse G. Local expresssion of cytokines in rat bladder carcinoma tissue after intravesical treatment with Nocardia rubra cell wall skeleton and bacille Calmette-Guérin. Urol Res 25:19-24, 1997.

Roy M, Drouin P.,Dubuc-Lissoir J., Ehlen T., Ghatage P., Heywood M., Lotocki RJ, Murphy KJ, Schier, RM and Plante M. Human papillomavirus infections: guideline for investigation and management. SOGC Clinical Practice Guideline.J Soc Obstet Gynaecol Can 69:1-3, 1997.

1998

Roy M and Plante M. "Rapid-onset" cervical cancer is due to failures in screening program. J Lower Genital Tract Disease 2:2, 1998.

Lotocki RJ, Drouin P.,Dubuc-Lissoir J., Ehlen T., Ghatage P., Heywood M., Lotocki RJ, Murphy KJ, Schier, RM and Plante M. Management of the abnormalPapanicolaou smear. SOGC Policy Statement. J Soc Obstet Gynaecol Can 70: 57-74, 1998.

Plante M. and Roy M. Operative laparoscopy prior to a pelvic exenteration in patients with recurrent cervical cancer. Gynecol Oncol 69: 94-99, 1998. Lead article.

Dubuc-Lissoir J., Drouin P., Ehlen T., Ghatage P., Heywood M., Lotocki RJ, Murphy KJ, Schier, RM and Plante M. Guidelines for the laparoscopic management of the adnexal mass. SOGC Clinical Practice Guideline. J Soc Obstet Gynaecol Can 76: 1-8, 1998.

Plante M., Thomas GM, Swenerton K, Murphy JK, Brand AH and Rosen BP. Ovarian Cancer and You.Current Oncology: Ovarian Cancer Supplement. Vol 5, supp 2, November 1998.

Roy M and Plante M. Pregnancies after Radical Trachelectomy for early-stage cervical cancer. American Journal of Obstetrics and Gynecology. 179: 6: 1491-6, 1998.

1999

Wright VC, Drouin P.,Dubuc-Lissoir J., Ehlen T., Heywood M., and Plante M. Adenocarcinoma in situ of the cervix: clinical features and review of the literature. SOGC Clinical Practice Guideline. J Soc Obstet Gynaecol Can. 21(7): 699-706, 1999.

Dubuc-Lissoir J., Ehlen T., Heywood M. and Plante M. Prevention and treatment of thromboembolic disease in gynaecologic surgery. SOGC Clinical Practice Guideline.J Soc

Obstet Gynaecol Can. 21(11): 1087-94, 1999.

Plante M. Controverses dans la prise en charge du cancer de l'ovaire: L'ovariectomie prophylactique. Document publié par SmithKline Beecham Canada. 1-12, 1999.

2000

Ehlen T.,Dubuc-Lissoir J.,Brand A, Heywood M., and Plante M. Management of low malignant potential (LMP) tumours of the ovary. J Soc Obstet Gynaecol Can. 85: 19-21, 2000.

Brand, A., Dubuc-Lissoir J., Ehlen T,. and Plante M. Diagnosis of endometrial cancer in the assessment of endometrial bleeding. J Soc Obstet Gynaecol Can. 86:102-4, 2000.

Roy M et Plante M. La trachélectomie vaginale élargie pour cancer invasif du col utérin. J Gynecol Obstet Biol Reprod 29:279-281, 2000.

Renaud MC, Plante M and Roy M.Combined laparoscopic and vaginal radical surgery in cervical cancer. Gynecol Oncol 79: 59-63, 2000.

Elit, L., Plante M., Bessette, P., Ehlen T.,Rosen B, Heywood M.,and Stuart, G. Surgical management of an adnexal mass suspicious for malignancy. J Soc Obstet Gynaecol Can 22: 964-8, 2000.

Hoskins P, Eisenhauer E, Vergote I, Dubuc-Lissoir J, Fisher B. Grimshaw R, Oza A, Plante M, Stuart G, Vermoken J. Phase II feasibility study of sequential couplets of Cisplatin/Topotecan followed by Paclitaxel/ Cisplatin as primary treatment for advanced epithelial ovarian cancer. A National Cancer Institute of Canada clinical trials group study. J Clin Oncol 18 : 4038-44, 2000.

2001

Renaud MC and Plante M. Medical treatment of endometrial carcinoma in premenopausal woman wanting to preserve her ability to have children. A review. J Soc Obstet Gynaecol Can 23 : 213-9, 2001.

2002

Trudeau M, Stuart G, Hirte H, Drouin P, Plante M, Bessette P, Dulude H, Lebwohl D and Seymour L. A phase II trial of JM-216 in cervical cancer: A National Cancer Institute of Canada clinical trials group study. Gynecol Oncol 84 : 327-331, 2002.

Renaud MC, Plante M, Roy M. Ovarian thecoma associated with a large quantity of ascites and elevated serum CA 125 and CA 15-3. J Obstet Gynaecol Can. 2002;24:963-5.

Plante M. New opportunities to preserve fertility in cancer treatment. J Obstet Gynaecol Can. 2002;24(2):115-20.

2003

Plante M, Renaud M-C, Tetu B, Harel F, Roy M. Laparoscopic sentinel node mapping in early-stage cervical cancer. Gynecol Oncol. 91 :494-503, 2003.

Stehman FB, Rose PG, Greer BE, Roy M, Plante M et al. Innovations in the treatment of Invasive Cervical Cancer. Cancer (suppl) 2052-2063, 2003.

Renaud M-C, Plante M, Roy M. Metastatic gastrointestinal cancer presenting as ovarian carcinoma. J Soc Obstet Gynaecol Can. 25 : 819-24, 2003.

2004

Plante M, Renaud M-C, Harel F, Roy M. Vaginal Radical trachelectomy: an oncologically safe fertility-preserving surgery. An updated series of 72 cases and review of the literature. Gynecol Oncol 94 : 614, 2004.(lead article).

Plante M, Renaud MC and Roy M. Sentinel node evaluation in gynecologic cancer. Gynecol Oncol 18 : 75-87, 2004.

Tanguay C, Plante M, Renaud M-C, Roy M et Tetu B. Vaginal radical trachelectomy in the treatment of cervical cancer of the uterus: the role of frozen section. Int J Gynecol Pathol 23:170-5, 2004.

Dubé V, Veilleux C, Plante M, Tetu B. Primary villoglandular adenocarcinome of cloagenic origin of the vulva : a case report. Human Pathol 35:377-9, 2004.

Duguay Y, McGrath M, Lépine J, Gagné JF, Hankinson SE, Colditz GA, Hunter DJ, Plante M, Têtu B, Bélanger J, Guillemette C, De Vivo I. The functional UGT1A1 promoter polymorphism decreases endometrial cancer risk. Cancer Research 64 : 1202-07, 2004.

Lépine J, Bernard O, Plante M, Têtu T, Labrie F, Bélanger A, Guillemette C. Specificity and regioselectivity of the conjugation of estradiol, estrone and their catecholestrogen and methoxyestrogen metabolites by human UGTs expressed in endometrium. J Clin Endocrinol Metab 89 : 5222-32, 2004.

Rouleau I, Dorval M, Chiquette J, Plante M, Simard J and members of INHERIT BRCAs. Use of hormone replacement therapy (HRT) among women at high risk of hereditary breast and ovarian cancer undergoing BRCA1/2 genetic testing. JOGC 26 : 1059-66,2004.

2005

Plante M, Renaud M-C, Hoskins I, Roy M. Vaginal Radical trachelectomy:a valuable fertility-preserving surgery for early-stage cervical cancer. A series of 50 pregnancies and review of the literature. Gynecol Oncol, 98 : 3-10, 2005 (lead article)

J. Riopel, M. Plante, M-C. Renaud, M. Roy, B. Têtu. Lymph node metastases in low grade endometrial stromal sarcoma. Gynecol Oncol, 2005 ;96 :402-6.

Dubé V, Roy M, Plante M, Renaud MC, Têtu B. Mucinous ovarian tumors of mullerian-type. Analysis of 17 cases of borderline tumors, intra-epithelial, micro-invasive and invasive carcinomas. Int J Gynecol Pathol,24:138-46,2005.

Dorval M, Gauthier G, Maunsell E, Dugas MJ, Rouleau I, Chiquette J, Plante M, Laframboise R, Gaudet M,Bridge PJ,Simard J. No evidence of false reassurance among women with an inconclusive BRCA1/2 test results. Cancer Epidemiol Biomarkers Prev 14(12):1-6, 2005.

Fortin, J, Moisan A-M, Dumont M, Leblanc G, Labrie Y, Durocher F, Bessette P, Bridge P, Chiquette J, Laframboise R, Lépine J, Lespérance B, Pichette R, Plante M, Provencher L, Voyer P, Simard J.A New alternative splice variant of BRCA1 generated by an additional in-frame exon. Biochem Biophys Acta 1731 : 57-65, 2005.

Campos S, Seiden M, Oza A, Plante M, Potkul R, Hamid O, Lenehan P, Kaldjian E, Jordan C, Hirte H. A Phase 2, randomized, open-label, single agent study of CI-1033 administered at two dose levels in ovarian cancer patients who failed prior platinum based therapy. J Clin Oncol 23(24) : 5597-5604, 2005.

Vézina H, Durocher F, Dumont M, Houde L, Tranchant M, Chiquette J, Plante M, Laframboise R, Szabo C, Nevanlinna H, Stoppa-Lyonnet D, Goldgar D, Bridge P, INHERIT BRCAs and Simard J. Molecular and Genealogical Characterization of the R1443X-BRCA1 Mutation in High-Risk French-Canadian Breast/Ovarian Cancer Families. Hum Genet 117 : 119-32, 2005.

Plante M and Roy M. Radical vaginal trachelectomy : a fertility preserving option for young women with early-stage cervical cancer. Conference Report. Gynecol Oncol 99(3) : S143-6, 2005.

2006

Plante M and Roy M. Fertility-preserving surgery for cervical cancer. Oncology, 2006 (accepted for publication for April).

Goffin F, Plante M, Roy M. Fertility-preserving surgery for cervical cancer. CME Journal, 2006.

Plante M, Lau S, Brydon E, Swenerton K, Leblanc R. Roy M. Neoadjuvant chemotherapy followed by vaginal radical trachelectomy in bulky stage Ib1 cervical cancer : a case report. Gynecol Oncol. May 2006.

Popa I, Plante M, Renaud MC, Roy M. Negative sentinel lymph node accurately predicts status of pelvic lymph nodes in uterine cervix carcinoma. Gynecol Oncol 2006. accepted

Thibaudeau J, Lepine J, Tojcic T. Duguay Y, Pelletier G, Plante M, Brisson J, Tetu B, Jacob S, Perusse L, Bélanger A, Guillemette C. Charactererization of common UGT1A8, UGT1A9 and UGT2B7 variants with different capacity to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone. Cancer Res : 66, 125, 2006.

Avard D, Bridge P, Bucci LM, Chiquette J,Dorval M, Durocher F, Easton D, Godard B, Goldgar D, Knoppers BM, Laframboise R, Lespérance B, Plante M, Tavtigian SV, Vézina H, Wilson B, Simard and INHERIT BRCAs Partnering in Oncogenetic Research - The INHERIT BRCAs Experience: Opportunities and Challenges. Fam Cancer 5 :3013, 2006.

Pfisterer J, Plante M, Vergote I, du Bois A, Hirte H, Lacave AJ, Wagner U, Stähle A, Stuart G, Kimmig R, Olbricht S, Le T, Emerich J, Kuhn W, Bentley J, Jackisch C, Lück HJ, Rochon J, Zimmerman A, Eisenhauer E for the AGO OVAR, NCIC CTG and EORTC GCG*. Gemcitabine plus carboplatin versus carboplatin in patients with platinum-sensitive recurrent ovarian cancer. J Clin Oncol 2006.accepted

Bachvarov D, L'Espérance S, Popa I, Bachvarova M, Plante M, Tetu B. Gene expression profiling predicts therapeutic response to chemotherapy treatment in patients with serous papillary adenocarcinomas of the ovary. Internat J Oncol, 2006 accepted.

Moisan AM, Fortin J, Dumont M, Samson C, Bessette P, Bridge P, Chiquette J, Laframboise R, Lépine J, Lespérance B, Pichette R, Plante M, Provencher L, Simard J. No evidence of BRCA1/2 rearrangements in high risk French-Canadian breast/ovarian cancer families. Genetic Testing, submitted, 2006

Durocher F, Labrie Y, Soucy P, Sinilkova O, Labuda D, Bessette P, Chiquette J, Laframboise R, Lépine J, L'Espérance B, Pichette R, Plante M. Mutation analysis and characterization of ATR sequence vaiants in breast cancer cases from high risk french canadian breast/ovarian cancer families. Intern J Oncol 2006 (submitted).

Chapitres de livre

CHAPITRES DE LIVRE

1995

Roy M and Plante M. The staging of vulvar cancerIn:Papillomavirus in Human Pathology. Série Ares-Serono Symposia Publications,Raven Press,New York.Editor:J.Monsonego. Volume 9, p.427-435, 1995.

1996

Plante M. Role of tumor markers in cervical cancer.In: Cervical Cancer and Preinvasive Neoplasia. Editors: William Hoskins and Stephen Rubin.Lippincott-Raven,NewYork.First Edition,p.371-380,1996.

1997

Plante M and Roy M. Radical Trachelectomy: Surgical Technique. In: Operative Techniques in Gynecologic Surgery. Editor: David Gershenson. WB Saunders Co, Philadelphia, 2(3):187-199,1997.

1999

Gastl G and Plante M. Interleukin-6 levels in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer. In: Methods in Molecular Medicine, Ovarian Cancer, 1999.

Roy M and Plante M.Radical Trachelectomy for invasive cervical cancer. In:Laparoscopic Surgeryin Gynecological Oncology. Editors: Querleu D.,Childers, JM and Dargent D. Blackwell Science, Oxford. First Edition, pp 78-82, 1999.

Plante M and Roy M. Pregnancies following radicaltrachelectomy for the treatment of early-stage cervical cancer. In: 7th Biennial Meeting of the International Gynecologic Cancer Society, Editors: Pecorelli S, Atlante A, Benedetti Panici P, et al.,Monduzzi Editore, Bologna; pp 449-453, 1999.

2000

Dargent D and Plante M. Laparoscopic Surgery in Gynecologic Cancer.In: Principles and Practice of Gynecologic Oncology. Editors: William J. Hoskins,Carlos A. Perez and Robert C.Young. Lippincott Williams & Wilkins, 3rd Edition, pp 265-295, 2000.

Plante M. Fertility preservation in the management of gynecologic cancers.In: Current Opinion in Oncology. Editors: Montz FJ. Lippincott Williams & Wilkins. Vol 12 (5), 497-507, 2000.

2001

Plante M. and Roy M. New approaches in the surgical management of early stage cervical cancer.In: Current Opinion in Obstetrics and Gynecology. Editors: Grendys EC.Lippincott Williams & Wilkins. Vol 13 (1), 41-46, 2001.

Plante M and Roy M. Vaginal Radical Trachelectomy. In: Gynaecological Oncology: An Atlas of Investigation and Surgery. Editors: JR Smith, G Del Priore, J Curtin and JM Monaghan. Martin Dunitz Publishers, The Livery House. London. 81-9, 2001.

Plante M, Renaud MC and Roy M. Flaws in the use of neoadjuvant chemotherapy in advanced ovarian cancer. In: 8th Biennial Meeting of the International Gynecologic Cancer Society, Editors: Monduzzi Editore, Bologna;197-201, 2001.

Plante M, Renaud MC and Roy M. Exploratory laparoscopy prior to a planned pelvic exenteration. In: 8th Biennial Meeting of the International Gynecologic Cancer Society, Editors: Monduzzi Editore, Bologna;135-9, 2001.

2002

Roy M, Plante M and Renaud M-C. Fertility preserving treatments for early-stage cervical cancer. In : 3rd World Congress on Controversies in Obstetrics, Gynecology and Infertility. Eds : Z Ben-Rafael, R Lobo, Z Shoham, Monduzzi Editore, Bologna, 345-50, 2002.

Roy M and Plante M. Fertility preserving surgery for cervical cancer. In : Proceedings of the XI International Congress of Cervical Pathology and Colposcopy. Eds : J Cortes Bordoy and R Labastadi Nicolau, Monduzzi Editore, Bologna, 59-61, 2002.

2003

Roy M and Plante M. Laparoscopically assisted vaginal radical hysterectomy. In : Atlas of procedures in Gynecologic Oncology. Eds : Levine DA, Barakat RR and Hoskins WJ. Martin Dunitz Publishers, The Livery House. London, 193-205, 2003.

Plante M and Roy M. Vaginal radical trachelectomy. In : Atlas of procedures in Gynecologic Oncology. Eds : Levine DA, Barakat RR and Hoskins WJ. Martin Dunitz Publishers, The Livery House. London. 207-221, 2003.

Plante M. Fertility preservation in the management of cervical cancer. In :CME J Gynecol Oncol. Bosze P Ed and Roy M Guest Ed, vol 8 : 128-38, 2003.

Renaud MC, Plante M, Roy M. Fertility preservation in endometrial cancer. In : CME J Gynecol Oncol. Bosze P Ed and Roy M Guest Ed, vol 8 :121-27, 2003.

2004

Plante M. Laparoscopic vaginal radical trachelectomy. In : Vaginal and Laparoscopic Surgery. Eds : Dargent D, Querleu D, Plante M and Reynolds K. Taylor & Francis Publishers, London ; pp 187-200, 2004

2005

Roy M, Plante M, Renaud MC. Laparoscopically assisted radical vaginal hysterectomy. Best Practice & Research Clin Obstet Gynecol, Eds : Elsevier Publisher, vol 19, no 3, chapter 5, pp 377-386, 2005.

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